In this joint webinar, Eric Offermann and Bernd Zeiss speak about Nitrogen Dioxide (NO2) as a new sterilization method and an alternative to EtO gas. A joint study carried out by Gerresheimer, Sterigenics and Früh, shows that NO2 is well suited to terminally sterilize prefilled ophthalmic syringes. The following topics will be addressed in detail:
- Comparison of EtO vs. NO2 penetration into the filled syringe.
- Analyze gas ingress through different plunger stoppers including silicone oil-free and standard rubber plungers.
- Scrutinize gas ingress through two different cap designs based on different elastomer properties.
- Investigate gas permeation through COP plastic barrels compared to glass.
- Check if the final blister has an influence on either sterilization method.
